Gaultherin

Gaultherin

Gaultherin, which is the methyl ester of 2 – [(6-O-beta-D-xylopiranosil-beta-D-glucopyranosyl) oxy] benzoic acid is a glucoside contained in the bark of a plant of the betulaceae (Betula lenta L .) and in other species such as Polygala vulgaris L ..
This substance that has a brute or molecular formula: C16H26O12 is endowed with stimulating, diaphoretic, anti-asthmatic, anti-inflammatory properties, etc.
One of the main factors limiting the use of non-steroidal anti-inflammatory drugs is gastrointestinal toxicity.
Gaultherin has been shown to have analgesic and anti-inflammatory effects but lacks the gastric ulcerogenic effect as for aspirin.
According to a research, gaultherin, as an anti-inflammatory, does not cause ulcerative effects as it releases the relative salicylate in the intestine slowly, not in the stomach and left unchanged the cyclooxygenase-1, which was the source of cytoprotective prostaglandins in the gastric epithelium.

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