Cinchonine

Cinchonine

Cinchonine whose term in the IUPAC nomenclature is: (S) – [(2 R, 4 S, 5 R) -5-etenyl-1-azabiciclo [2.2.2] octan-2-yl] (quinolin-4-yl ) methanol is an alkaloid with a brute or molecular formula: C19H22N2O.
Cinchonine is an alkaloid present in Cinchona officinalis and is used in asymmetric synthesis in organic chemistry.
It is a stereoisomer and pseudo-enantiomer of cinconidine.
From the physical point of view, cinchona appears as a colorless and bitter powder.
It is a compound with a chemical structure similar to quinine, from which it differs only in the absence of a methoxy group on the quinolinic ring, and is the stereoisomer of cinconidine.

The Cinchonine, as well as in the Cinchona officinalis, is contained in the bark of plants of the genus Cinchona, together with other alkaloids such as quinine, quinidine and cinchonidine.
Cinchonine was used, especially in the past, in medicine as an antimalarial drug instead of quinine, but it is now out of use due to its scarce availability and too short-term effect.

Warning: The information shown is not medical advice and may not be accurate. The contents are for illustrative purposes only and do not replace medical advice.