Hispidulin, whose term in the official IUPAC nomenclature is: 5,7-dihydroxy-2- (4-hydroxyphenyl) -6-methoxy-4H-1-benzopyran-4-one is a natural flavone with a brute or molecular chemical formula : C16H12O6.
Hispidulin is in particular monomethoxiflavone derived from scutellar and methylated in position 6. It plays a role as an inducer of apoptosis, an anti-inflammatory agent, an antioxidant, an anticonvulsant, an antineoplastic agent and a plant metabolite.
Hispidulin is present in the plant world; among the various species it is found in some plants such as: Plantago major, Grindelia argentina, Arrabidaea chica, Saussurea involucrate, Crossostephium chinense, Artemisia and Salvia.
This natural flavone has potential antiepileptic activity experienced in rats and gerbils.
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