Nerolidol, or peruviol, is a sesquiterpene found in the essential oils of many types of plants and flowers.
This sesquiterpene has a brute or molecular formula: C15H26O and occurs naturally in two isomeric forms, cis and trans, which differ in the geometry around the central double bond.
Nerolidol is found in neroli, ginger, jasmine, lavender, tea tree, cannabis sativa, and lemongrass.
Nerolidol being one of over 40,000 terpenes present in nature, it is found in many plant species that produce floral aromas and also in various herbs used in traditional medicines.
Many plants produce nerolidol as a secondary metabolite. It develops in the bulbs, seeds, leaves and aerial parts of numerous species. This terpene plays a protective role against predatory herbivores that would otherwise devour the plants.
The trichomes of cannabis flowers also produce this sesquiterpene, which characterizes the taste and aroma of some varieties.
Nerolidol, with its strong and pleasant smell, is used for numerous cosmetic and cleaning products.
The fresh aroma of nerolidol is found everywhere, from shampoos and perfumes to soaps and detergents. The U.S. Food and Drug Administration has classified nerolidol as a safe food flavor, and you can in fact find it as a flavor enhancer in many food products.

Research conducted on cellular and animal models suggests that nerolidol exerts a myriad of therapeutic effects:
– Anti-inflammatory;
– Antinociceptive;
– Antitumor;
– Antioxidant;
– Neuroprotective;
– Antiulcer.
Neriodiol seems to synergize with some cannabinoids, improving their medicinal properties in a phenomenon known as the “entourage effect”. So far, research has found that this terpene enhances the sedative potential of CBN.

Warning: The information shown is not medical advice and may not be accurate. The contents are for illustrative purposes only and do not replace medical advice.

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